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Principle and Application of Ultrasonic Extraction

  • 2021-05-31
Ultrasonic extractor is also called ultrasonic assisted extraction, ultrasonic extractor. Utilize the strong cavitation, disturbance effect, high speed, breaking, stirring and other multi-level effects produced by ultrasonic radiation pressure to increase the frequency and speed of material molecular movement, increase solvent penetration, and accelerate the target component to enter the solvent to promote extraction.
Application analysis of ultrasonic extraction technology in the pharmaceutical field:
(1) Accelerate the movement of medium particles. When the frequency of ultrasonic waves in a continuous medium (such as water) is higher than 20khz, according to the Huygens wave principle, the medium particles (including the particles of the important effective components of medicinal materials) will move in the wavefront plane and propagate, causing the medium particles to move. , Can obtain huge acceleration and kinetic energy. The acceleration of particles can be calculated as more than two thousand times the acceleration of gravity. Because the ultrasonic energy acts on the active ingredient particles of the medicinal materials, the medium particles obtain huge acceleration and kinetic energy, and quickly leave the medicinal materials matrix and free in the water.
(2) Air operations. The propagation of ultrasonic waves in liquid media will produce special cavitation effects. Cavitation continuously produces a large number of small pores, and the internal pressure reaches thousands of atmospheres. The continuous "blasting" produces a weak shock wave effect on the Chinese herbal medicine, so that the components and materials of the Chinese medicine can escape under a certain pressure. Shelling, the foundation of the medicine Continuously eroded. The medicinal ingredients that are not part of the plant structure are continuously separated. Speed up the extraction of plant active ingredients.
(3) The homogenization of ultrasonic vibration makes each point in the sample medium have the same effect, and the whole sample is extracted more uniformly. To sum up, under the action of ultrasonic field, the effective substances in traditional Chinese medicine can not only be used as medium particles to obtain their own huge acceleration and kinetic energy, but also can obtain powerful external shocks through the "cavitation effect, and completely separate them."

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