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The principle of ultrasonic cell disruptor extraction and disruption

  • 2021-10-11
The so-called ultrasonic wave generally refers to the sound wave with a frequency range of 20k~10MHz, and its application power in the chemical field mainly comes from the ultrasonic cavitation effect. The cavitation effect produced by ultrasonic energy in the liquid, accompanied by strong shock waves and micro-jets with a velocity higher than 100m/s, the high-gradient shear of shock waves and micro-jets can generate hydroxyl radicals in the aqueous solution, and the corresponding physical effects Mainly mechanical effects (shock waves, micro jets, etc.), thermal effects (local high temperature and high pressure, overall heating), light effects (sonoluminescence) and activation effects (hydroxyl radicals generated in aqueous solution), Suzhou Sonic Ultrasonic Technology combines four effects It is not isolated, but interacts and promotes each other to speed up the reaction process. The powerful shock wave energy is the instantaneous rupture of the biological cell wall, so that the biological cell releases its contents. Such as proteins, carbohydrates, alkaloids, amino acids, genetic material DNA, ribonucleic acid RNA, etc., for people to conduct scientific research and use. The typical application is the extraction of Chinese medicine ingredients, the extraction of black tea and green tea.

       Ultrasonic extraction mainly uses liquid cavitation, so any parameters that affect the cavitation effect, such as ultrasonic power, frequency, action time, and the nature of the extraction system, will affect the extraction effect. Ultrasound is used in the extraction process including solid-liquid extraction and liquid-liquid extraction. It is more effective than conventional methods such as heat treatment, mechanical stirring or changing pressure.

Application fields of ultrasonic cell disruptor:

Application areas:
 ●Life Science--
﹣Bacteria, virus, spores and other cell structure decomposition, crushing, leaching, extraction
﹣DNA and protein extraction
﹣The fragmentation and decomposition of organelles
 
●Agricultural Science--
﹣The crushing, leaching and extraction of plant cells
﹣Dispersion and mixing of gold powder in genetic engineering
﹣Dispersion, degassing and extraction of food samples before testing
 
●Materials Science/Cosmetics Industry--
﹣Emulsification, homogenization, disintegration, and crushing of granular materials
-Dispersion and homogenization of carbon nanotubes, graphite selenium and other materials, ultrasonic liquid processing machine contains words-confidential:

 
●Medical Pharmacy--
﹣Liquefaction and fragmentation of tissues, disintegration of organelles
﹣Dispersion and extraction of Chinese medicine
﹣Degassing before sample chromatographic analysis

●Geology and mineral industry-
﹣Dispersion and extraction of soil and rock samples before analysis, ultrasonic cell crushing equipment
-Sample extraction, dispersion and crushing in non-ferrous metals and rare earth industries. Ultrasonic cell disruption equipment

●Environmental Science--
-Fragmentation, dispersion, homogenization, and emulsification of the sample before the detection of the target in the environmental sample. Ultrasonic cell crusher


●Biochemistry and chemical industry:
-Cell protein extraction, cell content extraction, alkaloid extraction, oil extraction, biological cell wall breaking, etc.;

●Chemical industry:
-Dispersion of molybdenum dioxide in engine lubricating oil, dispersion of silica, dispersion of metal sodium, microparticulation of sludge in oil, Suzhou Sonic Ultrasonic Technology Fuel Upgrading, Emulsification of Tanker Wastewater, Emulsification of Mineral Oil, Packaging Emulsification of waterproof coating agent, dispersion of titanium oxide in water; dispersion of writing graphite particles, dispersion of photosensitive materials, dispersion of fluorescent materials, dispersion of dyes in molten paraffin;

●Pharmaceutical industry:
﹣Dispersion of pharmaceutical substances for injection, extraction of Chinese herbal medicines, preparation of suspensions, preparation of seedlings, etc.; ultrasonic cell crusher


●Food industry:
﹣The dispersion of powder emulsion, the emulsification of ghee, the dispersion of raw materials in sauce manufacturing, the aging of wine, etc.; ultrasonic cell crusher

●Make-up industry:
-Emulsification of wax and paraffin, dispersion of fine particles in oils such as detergents and lotions, etc.; ultrasonic emulsifier

●Environmental protection industry:
﹣Sewage treatment, waste gas dust removal, anti-scaling, electroplating, etc.; ultrasonic emulsifier

●Other:
-Emulsification of rolling oil, extraction of bio-nano, emulsification of oleic acid, emulsification of adhesives, emulsification of epoxy resin, dispersion of ceramic raw materials, dispersion of pressure-sensitive paper agents.


        When a decentralized crushing rod can continuously provide several KW of output power, the decentralized system can continuously handle the capacity of KL per hour. Since the cell dispersion rod is applied under high power, in order to prevent the vibrator from being damaged due to excessive amplitude, the system adopts the technology of constant amplitude control.

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